Transgender is a general term applied to a variety of individuals, behaviors, and groups involving tendencies that diverge from the normative gender role (woman or man) commonly, but not always, assigned at birth, as well as the role traditionally held by society.
Transgender is the state of one's "gender identity" (self-identification as male, female, both or neither) not matching one's "assigned gender" (identification by others as male or female based on physical/genetic sex). "Transgender" does not imply any specific form of sexual orientation; transgender people may identify as heterosexual, homosexual, bisexual, pansexual, polysexual or asexual. The precise definition for transgender remains in flux, but includes:
"Of, relating to, or designating a person whose identity does not conform unambiguously to conventional notions of male or female gender, but combines or moves between these."
"People who were assigned a gender, usually at birth and based on their genitals, but who feel that this is a false or incomplete description of themselves."
"Non-identification with, or non-presentation as, the gender one was assigned at birth."
A transgender individual may have characteristics that are normally associated with a particular gender, identify elsewhere on the traditional gender continuum, or exist outside of it as "other," "agender," "intergender," or "third gender". Transgender people may also identify as bigender, or along several places on either the traditional transgender continuum, or the more encompassing continuums which have been developed in response to the significantly more detailed studies done in recent years.
Transsexualism is a condition in which a person identifies with a physical sex different from the one that they were born with or assigned in cases where ambiguity of the child's sex organs led to assigning them a physical sex. Transsexualism is considered a taboo subject in many parts of the world and has become more widely known in Western nations in the late 20th century due to the sexual revolution, but remains a highly controversial topic. Negativism and discrimination about transsexualism may stem from religious beliefs or cultural norms. However, many cultures around the world and throughout time have not only held a place for transsexuals within their societies but even culturally sanction them, for example, the so-called two-spirit people in native American tribes.
~ Taken from Wikipedia
Not so much on CR anymore.