The two saddest tear jerking moments from two arguably one of the bittersweet series. Open the spoilers at your own risk, since it contains one of the biggest spoilers for the series. I have included a youtube link of the scene if you wanted as well.
Honey & Clover - Hanamoto and Rika
This is after when Hanamoto and Rika have lost Harada, their best friend (husband as well for latter) after a car crash. As Hanamoto tries to stop Rika from committing suicide after losing her husband, as well as being permanently crippled, when he sees her in perpetual pain on top of a building, he decides to end it all. As his hands were about to push her, she notices him, and he realizes what he was about to do. Despite being only a flashback, this is arguably one of the saddest scene in any anime.
Unfortunately, as of now, there is no video for that full particular scene, so if you want to see it, fastforward to 5:03 to 7:34 of the video: http://www.youtube.com/watch?v=L7N7MZE4MdM
Clannad After Story - Tomoya
This is as Tomoya and Ushio come back home by train, as he tries to describe Nagisa, his late wife, to his daughter. As he tries to reminisce about her, his grievance towards her causes tears to fall abruptly, unable to stop. The scene is powerful enough to make you feel sympathetic for him, even if you haven't watched the series yet.
Here's the video of the scene if you want to see that badly: http://www.youtube.com/watch?v=XJSCFO-7ng0
yeah!!! i really really like the tomoya "crying" scene!!! the anime made me cry !!!!!!