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Post Reply BRCA1 gene increases risk of cancer
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Posted 3/28/15
Anyways, yeah those people are saying her actions are illogical since everyone is at risk of cancer in some way and people can reduce their risk just by living a healthy life style, permanently destroying your body should be a last resort. My forensic professor said that it was better for her to get the surgery now before she is diagnosed with cancer, which by then might have been too late seeing that her mother, aunt and grandmother died of the same thing.

Tsuchimikado wrote:

10 bucks on the people who are "outraged" are guys that drooled all over her.
There was literally a comic that talks exactly about what you said and I have also read those posts under some articles, but to be fair the comment I paraphrased was from a women.
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Posted 3/28/15 , edited 3/28/15
I more concerned about whether or not she's leaning towards carcinophobia. Considering her family history, it wouldn't be surprising if Angelina harbors an abnormally elevated fear of cancer.
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Posted 3/28/15

Sogno- wrote:

gosh how dare she do something for herself that affects absolutely nothing about me



Yeah, I know, right? What she did; do you know how much that affects me and every other American? Do you? It affects us, like, not at all. Argh, the nerve of her!! *rips out hair and then throws his hands up in the air*
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Posted 3/28/15
Why I would be upset? I don't mind what she did. I mean, it is her body and therefore it is her decision, a decisin that afect no one but her. So it's nothing of my business.
Posted 3/28/15

Sogno- wrote:

gosh how dare she do something for herself that affects absolutely nothing about me


You have deceived me.
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Posted 3/28/15 , edited 3/28/15

FlyinDumpling wrote:

Anyways, yeah those people are saying her actions are illogical since everyone is at risk of cancer in some way and people can reduce their risk just by living a healthy life style, permanently destroying your body should be a last resort. My forensic professor said that it was better for her to get the surgery now before she is diagnosed with cancer, which by then might have been too late seeing that her mother, aunt and grandmother died of the same thing.

Tsuchimikado wrote:

10 bucks on the people who are "outraged" are guys that drooled all over her.
There was literally a comic that talks exactly about what you said and I have also read those posts under some articles, but to be fair the comment I paraphrased was from a women.


Sounds like people don't understand how awful it is to treat cancer once you get it. That's like saying preventative measures are not okay when it comes to cancer when it is okay for a bunch of other illnesses. Those people also do not have such a heightened risk so they don't seem to understand the real gravity of the situation.

Sure, perhaps the best way to deal with the issue is debatable, but the point is it is not a clear cut issue.
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Posted 3/28/15
I generally don't pay much attention to what such-and-such a celebrity does or isn't doing-- too much fodder taking up airtime and brain cells instead of real news and information. However, I'd be curious what the nature of the opposition to Ms. Jolie's actions is. If it's based upon some idea that cancer prevention is purely a matter of lifestyle and she's "disfiguring" herself unnecessarily or somehow doing something "anti-woman," then I'd say harmful ignorance is definitely on the part of the opposition.

As I understand it, she has a bad BRCA1 mutation, and has an extremely elevated risk of developing breast or ovarian cancer-- something like almost 50:50 during her lifetime. While in general, healthy living can reduce one's risk of cancer (and really should be encouraged as a course of action for everyone to the degree reasonable and possible-- better to prevent it in the first place to the degree possible than to treat it afterwards), it won't do much to blunt the effects of such a mutation. Prophylactic mastectomy and oophorectomy is a reasonable option for someone in her situation. The procedures won't reduce her risk to zero (indeed nothing does-- except death itself!), but they will greatly reduced her risk from here on out. As I understand it, though, since the risk of BRCA1 mutation carriers to develop cancer isn't absolute, and there are reasonably effective screening and early detection measures for breast cancer, and it has been shown that in many cases more limited breast conserving therapies (i.e. lumpectomies to just remove the tumor and some surrounding tissue) have the same survival as complete mastectomies, prophylactic mastectomy is not outright recommended-- it is merely presented as an option for carriers. Oophorectomy is generally recommended, though, for carriers once childbearing is done as ovarian cancer is very difficult to detect early on.

In the medical community, there is discussion of something called the "Angelina Jolie effect." The good side of it is increased awareness of the disease (by which I mean breast cancer in general) and screening. The bad side is when people who do not have the same risk profile as Ms. Jolie undergo unnecessary testing, or undergo more radical surgery than is warranted while citing her as an example. It's perhaps not fair to name the "effect" thus as Ms. Jolie, as far as I know, isn't going around saying everyone should get double mastectomies or anything like that, but the name has stuck nonetheless.

Posted 3/29/15 , edited 3/29/15
She can still have sex right? I don't know much about how vaginas work. I mean, are any of us big enough to reach her eggs? I mean, even if you did have sex with her, it should feel the same, right?
Posted 3/29/15
This is completely outrageous. I can't believe she'd do such a thing.

#downwithangelina
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Posted 3/29/15
Sure, her body her choice, but what doesn't increase the risk of cancer nowadays?
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Posted 3/29/15

PeripheralVisionary wrote:

She can still have sex right? I don't know much about how vaginas work. I mean, are any of us big enough to reach her eggs? I mean, even if you did have sex with her, it should feel the same, right?
What makes you think you can ever have sex with her?
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Posted 3/29/15
It's amazing how many people want to second guess medical decisions based on a media frenzy.
Posted 3/29/15 , edited 3/29/15

FlyinDumpling wrote:


PeripheralVisionary wrote:

She can still have sex right? I don't know much about how vaginas work. I mean, are any of us big enough to reach her eggs? I mean, even if you did have sex with her, it should feel the same, right?
What makes you think you can ever have sex with her?


I didn't say that. I'm just asking if a woman should undergo such a procedure what a difference would be if they did have sex. That and I am not sexually attracted to Angelina Jolie for some odd reason. It's true. Pervy PeripheralVisionary is not all that attracted to Jolie.
Posted 3/29/15
I applaud her. If my grandmother was given that chance she would have taken it. She was just tested for that mutation. And we will find out if it's genetic. Of course it costs money, but since we have a big family we need to find out who is in risk. Jolie made a great decision, will Cancer occur to her, it's a possibility. But she reduced her chances. She has kids and is probably happy. It's a big decision to remove what she did. Does everyone have to go do that now? No but it's something to think about if Cancer runs in your family.
Posted 3/29/15
87% is too high for me. I'd remove it.
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