After an earthquake destroyed Xiang Qin's house, she and her father moved in with the family of her father's college buddy, Uncle Ah Li. To her surprise, the kind and amicable aunt and uncle are the parents of her cold and distant schoolmate Jiang Zhi Shu, a genius with an IQ of 200 whom not too long ago rejected her endless crush on him. Will the close proximity give her a second chance to win Zhi Shu's heart? Or, will her love for him end under his cold words? What happens when there is competition for his heart? ”

The sequel of It Started With A Kiss begins with Xiang Qin and Zhi Shu's wedding and honeymoon. Even after marriage, they experience problems and interferences within their marriage such as mistaken pregnancy, misunderstandings, and a run-in with a girl from Zhi Shu's past. Xiang Qin and Zhi Shu switch to medical school to become nurse and doctor. During that time, Zhi Shu meets new rivals who wish to outdo him and Xiang Qin makes four new friends, and one of them likes her and wishes to replace Zhi Shu.
How will their lives turn out to be?”