Shigeru Miyamoto recently stated that the Zelda development team is currently working on a new game, so naturally we'd love to see them making use of Wii MotionPlus. Of course, the main aspect of the game that simply has to have Wii MotionPlus control is sword fighting. It'd be nice if the main game stuck to the normal Zelda gameplay, but for some battles you can switch to a first-person perspective, giving you full control over where Link swings his sword. The fencing game in Wii Sports Resort is a fantastic example of how this could work. Add movement with the Nunchuk's analogue stick and you've got the Zelda swordfighting action that gamers have been dreaming of.
Of course, Link has more at his disposal than his trusty sword, and while some of his weapons won't really benefit much from the added abilities of Wii MotionPlus, others will be greatly improved. Imagine chucking a boomerang by actually making a throwing action (think the Frisbee game in Wii Sports Resort), or chucking bombs with just the right motion.