Monkey D. Luffy , a 17-year-old boy. He is the captain of the Straw Hat Pirates. He is portrayed as carefree and sometimes air-headed. He generally has a huge appetite, for meat in particular. By accidentally eating a Devil Fruit, a fruit that grants special abilities to those who eat them, his body gained the properties of rubber. Luffy's dream is to become the Pirate King. Luffy is voiced by Urara Takano in the original video animation (OVA) and by Mayumi Tanaka in the Japanese version of the anime.

Roronoa Zoro is the first to join the crew. He is 19 years old and a skilled swordsman, who uses up to three swords at once, clutching the third in his mouth. He is extremely poor at understanding geographical directions and gets lost very easily. He also sleeps a great deal and loves to drink. His goal is to become the greatest swordsman in the world. Zoro is voiced by Wataru Takagi in the OVA and by Kazuya Nakai in the Japanese version of the anime.

Nami is the crew's 18-year-old navigator and the second to join. Her navigation skills are excellent and she has the ability to recognize and analyze even the slightest changes in the weather through sheer intuition. She is also an excellent thief and pickpocket. Her dream is to draw a complete map of the world. Nami is voiced by Megumi Toyoguchi in the OVA and by Akemi Okamura in the Japanese version of the anime.

Usopp is the crew's 17-year-old marksman and the third to join. He is a chronic liar, talented inventor and has notable artistic talent, shown in his painting of the Straw Hat's Jolly Roger and crafting of detailed snow sculptures. Usopp's dream is to become a "brave warrior of the sea". Usopp is voiced by Kappei Yamaguchi in the Japanese version of the anime.

Sanji is the crew's 19-year-old chain-smoking chef and the fourth to join. He knows how it feels to starve from first hand experience. Therefore he will never refuse someone a meal and becomes easily agitated when food is wasted. He is obsessed with women and has a strong sense of chivalry. He will never harm a woman, no matter what. His dream is to find the All Blue, a legendary sea, containing every kind of fish in the world. Sanji is voiced by Hiroaki Hirata in the Japanese version of the anime.

Tony Tony Chopper is the crew's 15-year-old doctor and the fifth to join. He is a blue-nosed reindeer, who gained human properties by eating a Devil Fruit. He is capable of conversing with humans and animals alike. He is also very naïve and has a tendency to believe anything told to him. His dream is to create a cure for all the world's diseases. Chopper is voiced by Ikue Otani in the Japanese version of the anime.

Nico Robin is the crew's 28-year-old archaeologist and the sixth to join. She ate a Devil Fruit and gained the ability to create copies of any part of her body on surfaces in her proximity. She is extremely intelligent, having taught herself archeology at a very young age. Her dream is to find and decipher the Rio Poneglyph, an ancient stone telling a long lost part of history. Robin is voiced by Yuriko Yamaguchi in the Japanese version of the anime.

Franky is the crew's 34-year-old shipwright and seventh to join. He is a cola-powered cyborg. His artificial body grants him incredible strength, as well as making him practically invulnerable to most frontal attacks. It is equipped with countless weapons. Nevertheless, Franky is very sensitive and like Chopper has trouble hiding his emotions. His dream is to build a dream ship and sail it around the world, something he is now doing aboard the Thousand Sunny. Franky is voiced by Kazuki Yao in the Japanese version of the anime.

Brook is the crew's 88-year-old musician and eighth to join. He is a living skeleton, resurrected by means of a Devil Fruit. He has a strange personality, being a combination of a gentlemanly persona and a perverted, crude sort. He speaks in a dignified, educated manner at most times, while having amazingly bad manners. His goal is to circle the Grand Line and return to Reverse Mountain, fulfilling a 50 year old promise. Brook is voiced by Chō in the Japanese version of the anime.

Going Merry the crew's first ship, a caravel with a lamb's figurehead. She is a gift from a girl from Usopp's village after the Straw Hats saved their town from being raided by the Kuro's Pirates. Her dream is to travel with the Straw Hats forever. She endures many hardships throughout her time as a ship, but ultimately breaks apart, and is given a Viking funeral. While burning, she comforts the grieving Straw Hats by telling them that she is happy to have traveled with them and thanks them for taking care of her during their time together. It has been stated by Franky that the Merry's soul resides in their new ship, the Thousand Sunny. Also, Gate 2 of Franky's Soldier Dock System on the Thousand Sunny houses a miniature landing vessel called the Mini Merry 2 that resembles the Going Merry

Thousand Sunny is the crew's second major ship, a brigantine-rigged sloop-of-war with a lion's figurehead. She is built by Franky, and his dream is for her to travel to the end of the ocean. Thousand Sunny is twice as big as the Going Merry, and has a unique Soldier Dock System created by Franky, a rotating wheel with six compartments that allows her to allowing deploy whatever that is in the compartments. Franky has stated that it has the soul of the Going Merry, so it likely shares the Merry's dream of traveling to the end of the seas with the Straw Hats.