Angelique, an orphaned medical student living in Arcadia, receives a visit from Nyx (a benevolent billionaire who sits on the school board). Nyx tells that he is trying to form a group of magically talented combatants to fight against the monsters called Thanatos that have become increasingly violent. The purpose of Nyx's visit is to recruit Angelique into the team. He has read a newspaper article which reports that Angelique mysteriously cured a moribund man assaulted by Thanatos. Angelique turns down the offer, saying she cannot quit her school.

Later, Angelique meets Rayne who is wounded by fighting against Thanatos and treats him. A Thanatos starts assaulting the school. Nyx tells Angelique it is her obligation to use her power to save the world. Rayne and Nyx fight with the Thanatos and tell Angelique to flee, but seeing her injured friend, Angelique has a flashback of her childhood when her mother was killed by a Thanatos. Her strong prayer to save her friend expels the Thanatos. Suddenly, whole Arcadia is enveloped in aurora-like light born from inside Angelique, proving that she is the only female "purifier". Nyx tells her she is a future Queen, messianic figure believed by many to be able to save Arcadia. Many of her future collaborators look up the sky in anticipation of Queen's arrival.