Megumi Noda, or "Nodame," is a piano student at Momogaoka College of Music. Although she is an extremely talented pianist who can play by ear, she can't read music. She also hates to take a bath or clean her room. For her daily meals, she usually grabs something out of her friend's lunchbox.
Nodame soon falls in love with Momogaoka's top student, Shinichi Chiaki. Born into a musical family, he plays the piano and violin brilliantly. Although his major is piano, he has secret ambitions to become a conductor.
Based on the big hit comic book by Tomoko Ninomiya, this is the romantic comedy of two completely different personalities.