Saito, although he has not been seen on a lot of occasions, has also appeared in the film Ghost in the Shell for a split second with both his eyes present. He also appears in the manga, but has no major role with his Hawkeye on his right eye instead of his left. Saito has a video game appearance in the Stand Alone Complex PSP game as a main character alongside Motoko, Batou and Togusa, using his position as Section 9 sniper.
Saito had been mentioned by Motoko and Batou when they are talking to Togusa that he had no cyber implants on him. Saito only has his Hawkeye and left arm as artificial prosthetic with the rest of his body being natural, being needed for his sniper duties. His Hawkeye is not foolproof as it can be hacked by another party as proven when a rogue HAW-206 multi-ped think tank vehicle overwrites his Hawkeye use in order to confuse him.
He is also not patient with his team mates for most of the time when Saito is in Section 9-mandated operations with them, although he can be patient and cunning thanks to his mercenary combat experience in the field. Saito doesn't try to hide that he hates grunt work, but does so as he is a part of Section 9.
World War IV
Before Saito was recruited to serve in Section 9, he fought against American Imperial Army soldiers and various UN forces as a freelancer hired by various anti-occupation guerrillas during World War IV in South America, starting in Mexico when he joined up with Red Bianco, a unit made up of foreigners that wanted to free Mexico and the rest of South America from foreign occupation.
He lost his left eye and arm after engaging American, British and Japanese UN peacekeepers, who were coincidentally led by Motoko Kusanagi, in the destroyed city of Monterrey. After successfully picking off several of Motoko's men with his excellent sniper tactics, she cornered him in a tense showdown. Motoko bluffed Saito into thinking that, even though it was theoretically a hopeless contest between full human and full cyborg, she had not yet downloaded mid-range marksmanship software, and thus Saito was lured out, thinking he might have a chance to get a shot in at her. Saito's bullet grazed the Major's cheek, and her bullet traveled down the scope of his rifle, sending glass shards into his left eye; before Saito could reload, she was on top of him and stabbed a large combat knife through his left hand.
When a Tachikoma uncovered his cards after leaving a poker game between Section 9 and plain clothed officers, it whispered to the other officers that Saito could have been telling the truth after all, alluding that he was really attacked by Motoko Kusanagi in South America in his mercenary days.
Post-World War IV
In 2nd GIG, Saito would later recount that the Major's following order to not move at all was the first order he ever took from her.
In Solid State Society, Saito was missing through most of the movie because he was in Africa and later because his left arm was shot by another sniper; naturally, his shot was more accurate, severely wounding his target.
It was also revealed that Saito may have had more cyberizations done to him according to the conversation he had with Batou in the elevator, he may have had a better heart or lungs.