Blood-C, is an upcoming 2011 anime/manga series and 2012 film produced and collaborated by Studio Production I.G and manga creators CLAMP. This is Production I.G's second anime series related to the Blood franchise, the first being Blood+, which aired in 2005-2006.
The anime was announced in the May 2011 issue of Shōnen Ace magazine where it was revealed it will be a collaboration between Studio Production I.G and the manga creator group CLAMP where CLAMP will be creating the story and original character designs while Production I.G will be handling the animation. The anime is published by Aniplex and will be directed by Tsutomu Mizushima with Junichi Fujisaku, who previously worked on Blood the Last Vampire and Blood+, as his creative supervisor. Nanase Ohkawa will be supervising the scripts and co-writing them with Fujisaku while Kazuchika Kise is adapting CLAMP's character designs for animation and Naoki Sato is composing the music. The opening theme will be "spiral" performed by Ray Fujita's band DUSTZ. The anime will begin airing on July 8, 2011 on MBS and TBS.
A manga adaptation by Ranmaru Kotone will begin serialization in Shōnen Ace magazine on May 26, 2011.
A 2012 anime film will be made after the anime series.