On her first date with the cutest boy in school, Ichigo Momomiya is zapped by a mysterious ray that scrambles her DNA with that of the endangered Iriomote wildcat. The next day, Ichigo discovers that she has developed the agility (and occasionally the ears and tail) of a cat, as well as the power to transform into a pink-haired superheroine, Mew Ichigo. She and four other girls - each endowed with the genes of a different "Red Data" animal, have been selected for the top-secret Mew Project, which aims to protect the Earth from an alien menace known as Deep Blue.
Deep blue is the leader of aliens Kishu, Pai and Taruto, he promised to help their people if they destroyed the human race, for their peoples planet died, outcasting all the remaining aliens to an even more un-enhabitalble planet. Yet earth was created for them as their perfect planet yet humans have populated the planet and are destroying it bit by bit. The mew project was made by Ryou's father who was a scientist studying ancient times, but he and his wife were killed when their house mystyously set ablaze, leaving their only son Ryou alone, yet he carryed on with his fathers research with his fathers old partner. But when the research was finally done Ryou tested the animal ray on himself to test if it was safe, yet he didnt have the right blood type so he turned into an animal but he was able to turn back and also turn into an animal again but only for 10 minutes. When the aliens started attacking earth the Mew project started! Kishu was the first alien to attack, but he soon started to have feelings for his enemy Ichigo and that didnt go down well with Pai and Taruto. Using creatures called pedacites to do most of their fighting for them they gave the Tokyo Mew Mews a hard time yet both side kept fighting for the earth!