Tsunade (綱手, Tsunade) is the Fifth Hokage (五代目火影, Godaime Hokage; Literally meaning "Fifth Fire Shadow") of Konohagakure. She succeeded the position after the death of her teacher, Hiruzen Sarutobi. She, along with Orochimaru and Jiraiya, are recognised as "The Legendary Sannin of Konoha".
Tsunade is a former student of the Third Hokage. Tsunade and her former teammates, Jiraiya and Orochimaru, are known as the "Legendary Three Ninja" (, Densetsu no Sannin) or simply the "Sannin". The word "Hime" (, Princess) is often attached to Tsunade's name because she is the granddaughter of the First Hokage and the grandniece of the Second Hokage. Tsunade is well known for her extremely large sexy breasts, despite the fact that Jiraiya referred to her as "flat-chested Tsunade" during their childhood. Many people would love to see her naked because of her incredibly sexy appearance.
One of Tsunade's noteworthy possessions was an amulet that belonged to her grandfather, which is said to be valuable enough to "buy three gold mines and the mountains on top of them" as stated by Jiraiya. On her brother, Nawaki's, twelfth birthday, Tsunade gave the amulet to him in the hopes that it would help him achieve his dream of becoming Hokage. The next day, Nawaki died as one of the many casualties of the war going on at the time, and the amulet was returned to Tsunade's possession. Sometime afterwards, Tsunade fell in love with a man named Dan, who also wanted to become Hokage. As a sign of her affection and in the hopes that it would help him achieve his goal, Tsunade gave him the amulet as well. Dan too would go on to die a bloody death during the course of the war, once again returning the amulet to her possession.
With the deaths of the two she loved the most, Tsunade came to lose faith in the title of Hokage, believing that only fools would want such a position. With these changes of ideals, Tsunade left Konoha with Dan's niece, Shizune, taking the latter in as her apprentice.
Tsunade's name is taken from the character of the same name from Jiraiya Goketsu Monogatari (, "The Tale of the Gallant Jiraiya"). The Tsunade in that story excelled in slug magic and was married to Jiraiya. The name "Tsunade" () means "mooring rope."
The deaths of Dan and Nawaki greatly changed Tsunade; Dan's death and her failed attempt to save him gave her a fear of blood, causing her to freeze up when ever seeing it. The amulet's repeated returns to her also led her and many others to believe that it was cursed, and whoever Tsunade might give it to would die soon after.
Tsunade is also a compulsive gambler who has the unfortunate disadvantage of having terrible luck. As a result, she has been elevated to a comical status as "The Legendary Sucker" (, Densetsu no Kamo) for the gross profits others have made off her misfortune and gambling addiction. In the rare instances that Tsunade hits a winning streak, she believes it to be a bad omen, and bad things do tend to happen to her afterwards. The symbol on the back of her coat, (kake), means "gamble," or "wager," as gambling is one of her favorite pastimes.
Tsunade typically projects a tough demeanor, even when facing great personal difficulty, and rarely compliments or praises people. She readily criticizes others for their faults, such as Naruto for his immaturity or Jiraiya for his perversion. On occasion, though, Tsunade often shows sympathy for others, consoling Shikamaru that while he failed his mission to return Sasuke to Konoha, all of his teammates survived.