Yakushiji Ryōko no Kaiki Jikenbo (薬師寺涼子の怪奇事件簿, Yakushiji Ryōko no Kaiki Jikenbo? , lit. "Ryōko Yakushiji's Strange Case Files") is a series that consist of TV anime, mangas and light novels created by Yoshiki Tanaka and illustrated by Narumi Kakinouchi. Two Drama CDs had also been released prior to the anime adaptation with different seiyus from the CD and the TV version.
The series centers around Ryōko Yakushiji, an elite police officer with the Tokyo Metropolitan Police Department who had graduated from Tokyo University under its Law Faculty. She is involved with her subordinate Junichirō Izumida as they investigate cases that pertain to the paranormal and supernatural when and if they cannot be investigated with modern science.
As the light novels, manga, drama CDs and anime adaptation have different plots and paranormal events/creatures, their central plots are most of the time different from each other.